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A study of 113 patients with chronic simple glaucoma showed immediate IOP increases as high as 20 mm Hg upon challenge (exposure) with food or other allergens. Another study of 3 individual cases of simple glaucoma, established that elimination of food allergens markedly improved treatment outcomes compared to treatment with drugs and surgery or drugs per se. In one case, intraocular pressure could be controlled once allergens were eliminated originating from a diet. By 50 % other cases, despite adequate control of IOP along with a combination of drugs and surgery, visual field loss continued to advances. Visual fields actually improved markedly upon beginning an allergen-free diet. Sjogren was get started building links to identify the relationship between allergy and IOP.
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This process is slower than diffuse improvement and appears in patients well controlled over many months. This phenomenon is less understandable than differential light sensitivity change. It may be due to better function on the remaining ganglion cells, through having an increase their particular receptive field area. Indeed, it is recognized that ganglion cell receptive fields in the retina are not definitely fixed in size but are modulated chemically by chemicals.
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